If you like the latest and greatest regarding *OPTIMIZATION*, join Jim Brown as we interviewed one of the true LEGENDS in the space.
Dr. John Crisler.
Some of the things we discussed.
*AI's-when/if they are needed. Especially for older Men on Testosterone.
*Dr John's thoughts on Metformin
*Dr John just celebrated his 60th Birthday. How has anything changed if at all?
*Dr John's big picture perspective of the Optimization Landscape and how 'SICK CARE' is being changed.
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When it comes to the endocrine system, a lot of doctors who claim to practice evidence-based medicine don’t have any evidence at all. Why are so many patients struggling to get the data they need to improve their health? What strategies does it take to create a normal hormonal landscape in patients? When do AI’s become necessary, even for the most dialed-in men? On this episode, Dr. John Crisler goes deep on some of the intricacies and methodologies he uses for AI’s and anti-aging.
"The overall strategy is to create as normal a hormonal landscape as possible inside your body." -Dr John Crisler
- Estrogen lives in fat in high concentration. When you get rid of the fat, your insulin resistance goes down.
- The minimum effective dosage of an AI is 1/4 mg or 1/2 twice a week.
- Pregnenolone is great for anxiety. It’s nature’s own benzodiazepine.
- A lot of people quit Metformin too quickly, but you have to give it about 10 days to work.
- It will cause flatulence, nausea, etc. because it has to cleanse your microbiota first.
At the start of the show, we talked about how a lot of men aren’t even getting accurate data from the labs, and why it’s so hard for people to get their estrogen numbers right. We also talked about why men in their late 50s and 60s may need to take an AI. Next, we discussed how to make sure you have the right dosage of your AI.
We also discussed:
- How high estrogen can make you feel hotter than usual
- Why pregnenolone is great
- How to avoid letting yourself get old
As men age, the use of an AI will become more necessary. When your estrogen goes up, this will also affect your insulin resistance and weight, so using AIs to control it will really help. If you want to stay youthful, keep yourself limber so you don’t get stiff. Make sure you get a doctor who knows what they’re doing. Getting older doesn’t mean you can’t be in the best shape of your life!
Dr John Crisler is a world renowned author and expert on testosterone replacement therapy (TRT), having created several treatment protocols which have changed the way physicians everywhere care for their patients. There are good reasons why men have travelled to be seen by him from every state as well as dozens of foreign countries: "Dr John" successfully treats the tough cases. Go to drjohncrisler.com for more information.
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Brother...I'm not hiding this. I'm very open about my dosage and have been for years. 150 mgs per week either 3 IM shots or two depending on whether I"m using Prop or Cypionate. No AI. No hCG. Very simple and to the point. Metformin BID 1gm, NatureThroid 60mg AM, and 30mg PM.
AKKERNMANSIA = Microbiome = Metformin increases it! See here guys: Metformin Is Associated With
Higher Relative Abundance of
muciniphila and Several Short-
Chain Fatty Acid–Producing
Microbiota in the Gut
Diabetes Care 2017;40:54–62 | DOI: 10.2337/dc16-1324
Maybe one of the reasons why Gluten is so terrible for us guys is because it can raise PROLACTIN:
Patients taking Viagra are less likely to suffer a heart attack, new research claims.
Men taking the impotence drug were found to have a lower risk of having a heart attack or dying from heart failure than those not on the medication.
The findings mean Viagra could soon be used to treat hundreds of thousands of heart failure patients and even prevent fatal heart attacks, scientists say.
Experts from the University of Manchester studied 6,000 diabetic patients who had been given Viagra to treat erectile dysfunction.
The drug relaxes muscle cells in the blood vessels supplying the penis, allowing more blood to flow there.
This increased blood flow increases the likelihood of getting an erection.
Given the increasing reports of deaths in which the use of Viagra may be implicated, clinicians need to exercise caution when advising their patients with heart
Experts believe a key ingredient in Viagra called PDE5i, which relaxes blood vessels, also prevents damage to heart cells.
Heart failure is caused by the heart failing to pump enough blood around the body at the right pressure.
It most often occurs because the heart muscle has become too weak or stiff to work properly and is usually treated with medication which supports the heart.
Despite diabetics being prone to heart problems, the study participants did not suffer as many incidents as similar patients not on the drug.